Altered plasma pharmacokinetics of ceftiofur hydrochloride in cows affected with severe clinical mastitis
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چکیده
منابع مشابه
Altered plasma pharmacokinetics of ceftiofur hydrochloride in cows affected with severe clinical mastitis.
Mastitis is a frequent problem among dairy cows, reducing milk yield and increasing cull rates. Systemic therapy with the cephalosporin antimicrobial ceftiofur hydrochloride (CEF) may improve therapeutic outcomes, but the incidence of CEF violative residues has increased annually since 2011. One potential explanation is that disease status may alter the pharmacokinetics (PK) of CEF. To test thi...
متن کاملInvestigation the Efficiency Ceftiofur Hydrochloride in Prevention of Uterine Postpartum Infections and Improvement the Fertility Parameters in Holstein Dairy Cows Affected by Retained Fetal Membrane and Dystocia
Objective: Ceftiofur, a third-generation cephalosporin, is used as a usual antimicrobial drug in veterinary medicine. Positive efficiency of ceftiofur for treatment of retained fetal membrane (RFM) and acute puerperal metritis has been previously reported. Thus, this study was conducted to evaluate the efficiency of ceftiofur hydrochloride (CH) in prevention of uterine postpart...
متن کاملInvestigation the Efficiency Ceftiofur Hydrochloride in Prevention of Uterine Postpartum Infections and Improvement the Fertility Parameters in Holstein Dairy Cows Affected by Retained Fetal Membrane and Dystocia
Objective: Ceftiofur, a third-generation cephalosporin, is used as a usual antimicrobial drug in veterinary medicine. Positive efficiency of ceftiofur for treatment of retained fetal membrane (RFM) and acute puerperal metritis has been previously reported. Thus, this study was conducted to evaluate the efficiency of ceftiofur hydrochloride (CH) in prevention of uterine postpart...
متن کاملCharacterization of Haptoglobin Isotype in Milk of Mastitis-Affected Cows
Haptoglobin is a major acute phase protein in bovines and reportedly increases in serum and milk whey during mastitis, highlighting its potential as a diagnostic biomarker. Since haptoglobin is known to undergo tissue specific glycosylation resulting in different isoforms, this study was undertaken to characterize the isoforms of haptoglobin. Milk whey fraction and serum obtained from animals w...
متن کاملRandomized clinical trial to evaluate the efficacy of a 5-day ceftiofur hydrochloride intramammary treatment on nonsevere gram-negative clinical mastitis.
The objective of this study was to evaluate the efficacy of intramammary treatment with ceftiofur hydrochloride of nonsevere, clinical coliform mastitis. One hundred four cases on 5 farms met the enrollment criteria for the study. Escherichia coli was the most common coliform species identified in milk samples from cows with mild to moderate clinical mastitis, followed by Klebsiella spp. and En...
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 2016
ISSN: 0022-0302
DOI: 10.3168/jds.2015-10239